Endocrine Abstracts

ObjectiveTo determine the clinical, biological and etiological aspects of hirsutism.MaterialA retrospective study from 2009 to 2017 included 51 patients explored and followed for hirsutism in the endocrinology department of the Rabta hospital.ResultsThe mean age of hirsute patients was 29 years, their average age of menarche was 12 years old. Hirsutism appeared be...

Patients with polycystic ovary syndrome (PCOS) have features of the metabolic syndrome, including insulin resistance, obesity, and dyslipidemia, suggesting an increased risk for cardiovascular disease.ObjectiveTo assess the prevalence of metabolic syndrome in patients with a polycystic ovarian sydrome (PCOS).MaterialWe conducted a retrospective study including 51 patients with secondary...

IntroductionGraves’ disease is typically characterized by the presence of circulating autoantibodies that stimulate the TSH receptor, inducing hyperthyroidism and goiter. Hashimoto’s thyroiditis is an autoimmune disease leading to thyroid tissue destruction by cell and antibody-mediated immune processes. The development of Hashimoto’s thyroiditis following Graves’ disease is rarely reported. Its pathogenesis is not confirmed. Herein, ...

Introduction: Cardiovascular diseases are frequent in patients with hypopituitarism receiving conventional hormone replacement therapy. They represent the main cause of premature death in this population. Emerging evidence smggests that beyond traditional risk factors, evaluating coronary calcium score (CCS) and inflammatory markers such as high-sensitivity C-reactive protein (hs-CRP) provides valuable insights into cardiovascular health in this population. The aims of the pre...

Introduction: The insulin tolerance test (ITT) is the gold standard for hypothalamic–pituitary adrenal axis assessment. There are different protocols depending on the number and timing of serum samples. Our study aimed to investigate the kinetics of serum glucose and cortisol levels during ITT and to determine the most appropriate times for blood samples.Methods: Our study was cross-sectional and descriptive. One hundred patients with suspected adre...

Introduction: Insulin resistance is classically a feature of type 2 diabetes mellitus (T2D). It may also develop among patients with type 1 diabetes (T1D) increasing the risk of cardiovascular mortality. Metabolic syndrome (MS) reflects a state of IR. The aim of this study was to assess the frequency of MS in a population of young adults with T1D and compare it to healthy controls.Methods: We conducted a case control study including 68 T1D patients and 6...

Introduction: Patients with Sheehan’s syndrome (SS) may experience alterations in blood pressure (BP) regulation, possibly due to hormones deficiencies and hormone replacement treatment. The aim of the present study was to assess the 24h ambulatory BP in women with Sheehan syndrome.Methods: This was a monocentric cross-sectional study involving 50 women with complete anterior hypopituitarism secondary to SS and 50 age and body-mass index (BMI) match...

Introduction: Sheehan’s syndrome (SS) is characterized by a deficiency in pituitary hormone secretion. It is now being closely inspected for its implication in the onset of metabolic syndrome (MS). The aims of this study were to determine the prevalence of MS and assess its associated factors in women with SS.Methods: We carried out a cross-sectional study involving 50 patients diagnosed with SS and 50 controls, matched for age and body-mass index (...

Introduction: Carotid intima-media thickness (CIMT) is a simple and non-invasive method used to detect atherosclerosis. This measure could predict future cardiovascular events. Some studies have showed an increased cardiovascular in non functional adrenal incidentalomas (NFAI). The aim of this case control study was to determine the relationship between NFAI and CIMT.Methods: This case control study included 40 NFAI patients (16 men, 24 women, mean age 5...

Background: Non functional adrenal incidentalomas (NFAI) constitute the majority of adrenal tumors. This entity is a result of advances in imaging techniques and their prevalent use in clinical practice. Among the associated metabolic effects of NFAI, dyslipidemia emerges as a key factor, stimulating growing interest in understanding the link between these two entities.Methods: This case control study included 40 NFAI patients (16 men, 24 women, mean age...